Health & Wellness

The Best Bulk Quantity Facial Tissues

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Our picks are based on Amazon bestseller rankings, Amazon customer ratings, and product availability. We update our recommendations regularly to ensure accuracy.

Facial tissues are a household staple, essential for everything from managing allergies to wiping away tears. When buying in bulk, consider factors beyond just the count to ensure you're getting the best value and quality for your needs.

No. 1
Kleenex Professional Facial Tissue, Bulk, 48 Boxes x 125 Tissues (21606)
  • 125 Tissues/Box; 48 Boxes of Kleenex Professional Facial Tissue/Case; 6,000 Tissues/Case; 2-Ply; White; Flat Facial Tissue Boxes for Business
  • Kleenex is the #1 brand of facial tissue in North America, trusted by more consumers than any other.
  • Each Kleenex tissue is 2-ply, absorbent, soft and strong
  • Each tissue features smart innovations like an ultra-soft feel
No. 2
Amazon Basics Facial Tissue, 2-Ply, 640 Count (4 Packs of 160), (Packaging may vary)
  • SHIPMENT CONTAINS: 4 tissue boxes with 160 tissues per box (640 tissues total), perfect for bathrooms, living rooms, bedrooms, offices, and classrooms
  • SOFT AND STRONG: 2-ply facial tissues designed with two strong layers for ultimate care and comfort during everyday use
  • STYLISH DESIGN: Cube color combinations may vary, offering a clean look that complements any room decor
  • FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
No. 3
Kleenex Professional Facial Tissue, Bulk, 36 Boxes x 100 Tissues (21400)
  • 100 Tissues/Box; 36 Boxes of Kleenex Professional Facial Tissue/Case; 3,600 Tissues/Case; 2-Ply; White; Flat Facial Tissue Boxes for Business
  • Kleenex is the #1 brand of facial tissue in North America, trusted by more consumers than any other
  • Each Kleenex tissue is 2-ply, absorbent, soft and strong
  • Each tissue features smart innovations like an ultra-soft feel
No. 4
Amazon Basics Facial Tissue, 2-Ply, 2880 Count (18 Packs of 160), Packaging May Vary
  • SHIPMENT CONTAINS: 18 tissue boxes with 160 tissues per box (2,880 tissues total), perfect for stocking your home or office
  • SOFT AND STRONG: 2-ply facial tissues designed with two strong layers for ultimate care and comfort
  • VERSATILE USE: Perfect for bathrooms, living rooms, bedrooms, offices, and classrooms
  • FSC-CERTIFIED SKIN FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
SaleNo. 5
Kleenex On-The-Go Facial Tissues, 72 Travel Packs, 10 Tissues per Pack
  • WHAT’S INCLUDED — 72 packs of Kleenex On-the-Go Pocket Pack Facial Tissues, 3-Ply, 10 tissues per pack (3 trays of 24 travel packs, 720 tissues total)
  • PERFECTLY SIZED FOR ANY ADVENTURE — Don’t leave home unprepared. These Kleenex tissue packs are small enough to fit in pockets, purses, backpacks, or travel bags
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • SMALL BUT MIGHTY — This may be a convenient travel pack, but it contains the same ultra-absorbent, soft, and durable facial tissues that help runny noses and watery eyes, so you can be ready for anything
SaleNo. 6
Puffs Facial Tissues Ultra Soft, 4 Family Boxes, 124 Facial Tissues per Box, Allergies and Colds (Packaging...
  • Pack includes 4 Family Boxes (124 Tissues Per Box) of Puffs Ultra Soft Facial Tissues
  • Perfect size to stash anywhere
  • Gentle on sensitive skin
  • Made with cushiony thickness
SaleNo. 7
Puffs Facial Tissue Ultra Soft Non-Lotion, 8 Rectangle Boxes, 124 Facial Tissues per Box, Allergies and Colds...
  • RECTANGLE PACK CONVENIENCE: This pack includes 8 Rectangle Boxes of Puffs Ultra Soft non-lotion facial tissues, each containing 124 tissues, providing an essential supply for your household needs.
  • VERSATILE SIZE: These facial tissues are the perfect size to stash anywhere—whether it's in your car, office, or home—ensuring you’re always prepared for unexpected sniffles and sneezes.
  • GENTLE ON SKIN: Dermatologist tested, Puffs Ultra Soft facial tissues are designed to be gentle on sensitive skin, offering comfort without irritation during allergy or cold season.
  • CUSHIONY THICKNESS: Made with a cushiony thickness, these facial tissues provide a comforting touch for needy noses, making them ideal for everyday use.
No. 9
Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box
  • WHAT'S INCLUDED — 8 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 80 tissues per box (640 tissues total)
  • FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
  • SILKY SOFTNESS — These facial tissues are made with 3 layers and are silky soft for up to 100% irritation-free skin for an extra bit of comfort when you need it
  • ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
No. 10
Amazon Basics Ultra-Soft 3-Ply Premium Facial Tissues, 264 Count (4 Cube Boxes of 66) (Previously Presto!)
  • SHIPMENT CONTAINS: 4 Cube Boxes of facial tissues with 66 3-ply tissues in each box (264 tissues total)
  • ULTRA SOFT: Premium facial tissues offer durable strength and ultra softness for comfortable use on sensitive skin
  • VERSATILE DESIGN: Eye-catching colors and designs in convenient cube boxes for any room in your home or office
  • FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources

Last update on 2026-10-15 / Affiliate links / Images from Amazon Product Advertising API

How to Choose the Best Bulk Quantity Facial Tissues

Consider Tissue Count and Packaging

When purchasing facial tissues in bulk, the primary consideration is the total number of tissues you receive. Boxes often come in multi-packs, with each box containing a varying number of tissues. Evaluate whether you need individual small boxes for convenience or larger boxes for less frequent replacement. Some bulk options also offer larger cubes or pop-up dispensers, which can be more economical per tissue.

Material and Softness

The material composition significantly impacts the feel and performance of facial tissues. Look for tissues made from 100% virgin pulp for a softer, more absorbent experience. Some brands offer ultra-soft or lotion-infused options, which can be beneficial for frequent use or sensitive skin. Hypoallergenic and dermatologist-tested labels can indicate a gentler product.

Strength and Absorbency

While softness is important, the strength and absorbency of a tissue are crucial for its effectiveness. A good quality tissue should hold up without tearing easily, especially when wet. Consider the ply count; 2-ply or 3-ply tissues generally offer better strength and absorbency than single-ply options. This is particularly important for allergy sufferers or during cold season.

Environmental Considerations

For eco-conscious consumers, look for tissues made from sustainable sources, such as recycled materials or responsibly managed forests (FSC certified). Some brands also offer biodegradable or flushable options, though it's always best to check local plumbing guidelines before flushing. Packaging materials can also be a factor, with some brands opting for recyclable cardboard or reduced plastic.

Frequently Asked Questions

What is the typical ply count for bulk facial tissues?
Bulk facial tissues commonly come in 2-ply or 3-ply constructions. Higher ply counts generally offer increased softness, strength, and absorbency compared to single-ply options.
Are there hypoallergenic options available in bulk?
Yes, many brands offer hypoallergenic facial tissues in bulk quantities. These are typically free from harsh chemicals, dyes, and fragrances, making them suitable for sensitive skin and allergy sufferers.
How do I determine the best value when buying in bulk?
To find the best value, calculate the cost per tissue by dividing the total price by the total number of tissues across all boxes. Also, consider the quality and features like softness and strength in relation to the price.
Can I find eco-friendly bulk facial tissue options?
Absolutely. Look for tissues made from recycled content or certified sustainable wood sources. Some brands also focus on biodegradable materials and minimal, recyclable packaging.
What does 'lotion-infused' mean for facial tissues?
Lotion-infused tissues contain a moisturizing agent, often aloe or vitamin E, applied to the fibers. This helps to reduce friction and prevent skin irritation during use, offering a smoother, gentler experience.

How we compare Health & Wellness

1 Specifications: we compare the key features and specifications listed by the manufacturer and on Amazon.
2 Customer ratings: we take into account the average Amazon rating and the number of reviews.
3 Price: we check the current price and highlight notable deals.
4 Updates: comparisons are refreshed regularly as prices and availability change.

Our comparisons are reviewed and updated regularly to reflect the latest products and prices.

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