The Best Cough & Cold Medicine

Looking for the best Cough & Cold Medicine?

Discover now our comparison of the best Cough & Cold Medicine. It is never easy to choose from the wide range of offers. On the market, you will find an incalculable number of models, all at different prices. And as you will discover, the best Cough & Cold Medicine are not always the ones at the highest prices! Many criteria are used, and they make the richness and relevance of this comparison.
To help you make the best choice among the hundreds of products available, we have decided to offer you a comparison of the Cough & Cold Medicine in order to find the best quality/price ratio. In this ranking, you will find products listed according to their price, but also their characteristics and the opinions of other customers. Also discover our comparisons by categories. You won’t have to choose your products at random anymore.

SaleNo. 1

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. From the doctor recommended pain relief brand, the combo pack includes 16 Daytime and 8 Nighttime caplets for relief any time of the day
The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion and pressure
Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine.

SaleNo. 2

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

COUGH, COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast-Max Day Cold & Flu and Fast-Max Night Cold & Flu fast-dissolving liquid gels provides powerful multi-symptom relief for your worst cold and flu symptoms
SORE THROAT RELIEF: Both products contain Acetaminophen, which helps reduce fever and relieves sore throat, headache, and body pain
COUGH MEDICINE FOR ADULTS: Both products contain Dextromethorphan HBr, which helps suppress and quiet cough
CHEST CONGESTION RELIEF: Daytime cold medicine liquid gels contain Guaifenesin, an expectorant, which helps relieve chest congestion and thins and loosens mucus
NASAL DECONGESTANT: Both products contain Phenylephrine HCl, a nasal decongestant, which helps relieve stuffy nose, sinus pressure, & nasal congestion
NIGHTTIME COLD AND FLU MEDICINE FOR ADULTS: Nighttime liquid gels contain Doxylamine succinate, an antihistamine, which helps relieve runny nose & sneezing
TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend
FSA/HSA STORE ELIGIBLE MEDICATION: Save Up to 30%; Cover out-of-pocket expenses with pre-tax dollars (Product eligibility may vary by plan; Check with your benefits administrator to determine which expenses are eligible before you shop)
USAGE: Use as directed; For ages 12+ years
IQVIA using ProVoice Survey, August 2023; **U.S. News & World Report/Pharmacy Times 2023-2024

SaleNo. 3

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu
NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains
NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains
PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat
COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help

No. 4

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu

No. 5

Amazon Basic Care Severe Daytime Cold and Flu, Maximum Strength Liquid Cold Medicine, Non-Drowsy, Multi-Symptom Relief, for Adults and Children Age 6 and Over, Original, 12 fl oz (Pack of 1)

THE ACTIVE INGREDIENTS are acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), guaifenesin (expectorant) and phenylephrine HCl (nasal decongestant); compare to the active ingredients in Vicks DayQuil Severe Cold and Flu
SEVERE COLD AND FLU RELIEF: Temporarily relieves common cold and flu symptoms, such as headache, fever, sore throat, minor aches and pains, nasal and sinus congestion, sinus pressure, cough and chest congestion
MAXIMUM-STRENGTH PAIN RELIEVER AND FEVER REDUCER: This alcohol-free daytime medicine temporarily eases the discomfort caused by symptoms of the common cold and flu
NASAL DECONGESTANT: This cold medicine relieves nasal and sinus congestion and sinus pressure for non-drowsy relief
COUGH SUPPRESSANT AND EXPECTORANT: Amazon Basic Care Severe Cold and Flu temporarily relieves cough and helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus; makes coughs more productive

No. 6

Theraflu Severe Cold and Cough Medicine, Daytime and Nighttime Cough and Cold Medicine for Cough Relief, Berry Flavor - 8.3 Fl Oz x 2

Package contains one 8.3 fl oz bottle of Theraflu Severe Cold and Cough Daytime Cough and Cold Medicine, Berry Flavor and one 8.3 fl oz bottle of Theraflu Severe Cold and Cough Nighttime Cough and Cold Medicine, Berry Flavor
Delivers powerful pain relief and headache relief, along with relief from sore throat, fever and cough
Daytime and nighttime cough syrup formulations provide a unique warming sensation and delivers fast cough, cold and sore throat relief
Both syrups come in a delicious berry flavor
Nighttime adult cough syrup and sore throat medicine also contains an antihistamine to relieve runny nose and sneezing
Both cold and cough syrups contain acetaminophen 650 mg; daytime syrup also contains dextromethorphan HBr and nighttime contains Diphenhydramine HCI
Adults and children 12 years and older: take 30 mL of either daytime or nighttime cold medicine every four hours as needed for cold and cough symptom relief
HSA and FSA eligible product

No. 7

Amazon Basic Care Tussin Severe CF Max Syrup, Multi-Symptom Cough, Cold and Flu Liquid Medicine, Non-Drowsy, Relieves Cough, Sore Throat, Body Aches, Fever, Nasal and Chest Congestion, 8 fl oz

ACTIVE INGREDIENTS: This cold medicine contains a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant. Compare to the active ingredients in Robitussin Severe Multi-Symptom Cough Cold + Flu.
MAXIMUM STRENGTH: This cold medicine provides maximum strength relief of multiple cold and flu symptoms such as cough, nasal congestion, sinus congestion and pressure, minor aches and pains, sore throat, headache and temporarily reduces fever.
MUCUS RELIEF: Take this cold medicine to help loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive.
NON-DROWSY: This non-drowsy cold and flu medicine provides relief for adults and children age 12 years and over. Dosage cup included.
GREAT TASTING COLD MEDICINE: Amazon Basic Care Tussin CF Max, Multiple Symptom Cough Cold & Flu is gluten free, sugar free and alcohol free. Maximum strength claim based on maximum levels of active ingredients per 4 hour dose.

No. 8

Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks NyQuil Cold & Flu
RELIEVES COLD & FLU SYMPTOMS: Amazon Basic Care Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose
NIGHTTIME COLD AND FLU RELIEF: Amazon Basic Care Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.
EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.
GLUTEN FREE: This product is Gluten Free. Contains 10% ALCOHOL.

No. 9

Amazon Basic Care Nighttime Severe Cold, Flu and Cough Suppressant Medicine Powder, Pain Reliever/Fever Reducer, Nasal Decongestant, Antihistamine, Honey Lemon Infused with White Tea Flavors, 6 Count

ACTIVE INGREDIENTS: The active ingredients in Severe Cold, Flu and Cough are acetaminophen 650 mg, pain reliever/fever reducer; diphenhydramine HCl 25 mg, antihistamine/cough suppressant; phenylephrine HCl 10 mg, nasal decongestant which compares to Theraflu Severe Cold and Cough active ingredients.
FAST RELIEF: Severe Cold, Flu and Cough offers hot liquid therapy for fast relief of nasal and sinus congestion, cough, runny nose, sneezing, body ache, sore throat pain, headache and fever.
CONVENIENT PACKETS: Dissolve powder into 8 oz. of hot water and sip while hot for nighttime cold and flu relief. Take every four hours while symptoms persist.
COMFORTING WARMTH WITH GREAT TASTE: This flu medicine relieves pain with soothing honey lemon infused with white tea flavors.
ALCOHOL-FREE COLD AND FLU POWDER: This product contains no alcohol or gluten.

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Last update on 2025-03-06 / Affiliate links / Images from Amazon Product Advertising API

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