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The Best Cough & Cold Medicine

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Discover now our comparison of the best Cough & Cold Medicine. It is never easy to choose from the wide range of offers. On the market, you will find an incalculable number of models, all at different prices. And as you will discover, the best Cough & Cold Medicine are not always the ones at the highest prices! Many criteria are used, and they make the richness and relevance of this comparison.
To help you make the best choice among the hundreds of products available, we have decided to offer you a comparison of the Cough & Cold Medicine in order to find the best quality/price ratio. In this ranking, you will find products listed according to their price, but also their characteristics and the opinions of other customers. Also discover our comparisons by categories. You won’t have to choose your products at random anymore.

No. 1
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)
11,540 Consomer Reviews
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)
  • ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu
  • NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains
  • NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains
  • PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat
  • COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help
No. 2
Theraflu ExpressMax Severe Cold and Cough Medicine, Daytime and Nighttime Cough and Cold Medicine for Cough Relief, Berry Flavor - 8.3 Fl Oz x 2
  • Package contains one 8.3 fl oz bottle of Theraflu ExpressMax Severe Cold and Cough Daytime Cough and Cold Medicine, Berry Flavor and one 8.3 fl oz bottle of Theraflu ExpressMax Severe Cold and Cough Nighttime Cough and Cold Medicine, Berry Flavor
  • Delivers powerful pain relief, headache relief and nasal congestion relief, along with relief from sore throat, fever and cough
  • Daytime and nighttime cough syrup formulations provide a unique warming sensation and delivers fast cough, cold and sore throat relief
  • Both syrups come in a delicious berry flavor
  • Nighttime adult cough syrup and sore throat medicine also contains an antihistamine to relieve runny nose and sneezing
  • Both cold and cough syrups contain acetaminophen 650 mg and phenylephrine HCl 10 mg; daytime syrup also contains dextromethorphan HBr and nighttime contains Diphenhydramine HCI
  • Adults and children 12 years and older: take 30mL of either daytime or nighttime cold medicine every four hours as needed for cold and cough symptom relief
  • The nighttime syrup formula contains Acetaminophen 650 mg, Diphenhydramine HCl 25 mg, and Phenylephrine HCI 10 mg
SaleNo. 3
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
  • 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
No. 4
Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)
  • ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks NyQuil Cold & Flu
  • RELIEVES COLD & FLU SYMPTOMS: Amazon Basic Care Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose
  • NIGHTTIME COLD AND FLU RELIEF: Amazon Basic Care Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.
  • EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.
  • GLUTEN FREE: This product is Gluten Free. Contains 10% ALCOHOL.
SaleNo. 5
Mucinex Fast-Max Maximum Strength Cold & Flu Day and Night Medicine, All-in-One Multi-Symptom Relief Liquid Gels – 24 count (16 time + 8 time) (Packaging May Vary)
1,396 Consomer Reviews
Mucinex Fast-Max Maximum Strength Cold & Flu Day and Night Medicine, All-in-One Multi-Symptom Relief Liquid Gels – 24 count (16 time + 8 time) (Packaging May Vary)
  • MAXIMUM STRENGTH MUCINEX FAST-MAX COLD & FLU: Multi-Symptom Relief medicine; 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful medicine
  • DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day Time Cold and Flu helps reduce fever, relieve cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, minor aches and pains, headache and sore throat
  • NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Night Time Cold and Flu helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose and sore and itchy throat
  • # 1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand**
  • DAY TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever and Fever reducer; Dextromethorphan HBr - Cough Suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal Decongestant
  • NIGHT TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever/Fever reducer; Dextromethorphan HBr - Cough suppressant; Doxylamine succinate - Antihistamine; Phenylephrine HCI - Nasal Decongestant
SaleNo. 6
Mucinex Fast-Max & NightShift Combo Pack - Max Strength Cough & Cold Medicines For Mucus Relief, Chest Congestion, Nasal Congestion, Sinus Congestion, Sinus Pressure, Cough Symptom Relief (2x 6 FL OZ)
  • COUGH COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast Max Severe Congestion & Cough and NightShift Cold & Flu provides powerful multi-symptom relief for your worst symptoms
  • EXPECTORANT & DECONGESTANTS FOR ADULTS: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough has a Triple Action Formula that helps to relieve nasal & chest congestion, control cough & helps thin & loosen mucus to make coughs more productive
  • NIGHTTIME COLD AND FLU SYMPTOM RELIEF: Mucinex Nightshift Cold & Flu helps to reduce fever, relieve headache, minor aches and pains, sore throat, coughing, sneezing, & runny nose for a better morning
  • MUCINEX FAST-MAX SEVERE CONGESTION & COUGH ACTIVE INGREDIENTS: Dextromethorphan HBr - Cough suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal decongestant
  • MUCINEX NIGHTSHIFT COLD & FLU ACTIVE INGREDIENTS: Contains Acetaminophen - Pain reliever and fever reducer; Dextromethorphan HBr - Cough suppressant; Triprolidine HCl – Antihistamine
  • TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend
  • USAGE: Use as directed; For ages 12+ years
  • FSA & HSA Eligible: Save Up to 30%; Cover out-of-pocket expenses with pre-tax dollars; Product eligibility may vary by plan - Check with your benefits administrator to determine which expenses are eligible before you shop
  • IQVIA using ProVoice Survey, August 2023; **U.S. News & World Report/Pharmacy Times 2023-2024
No. 7
Vicks DayQuil and NyQuil Combo Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime And Nighttime Relief For Headache, Fever, Sore Throat, Cough, 72 Count, 48 DayQuil, 24 NyQuil Liquicaps
7,093 Consomer Reviews
Vicks DayQuil and NyQuil Combo Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime And Nighttime Relief For Headache, Fever, Sore Throat, Cough, 72 Count, 48 DayQuil, 24 NyQuil Liquicaps
  • FAST, POWERFUL MULTI-SYMPTOM RELIEF: Use non-drowsy DayQuil for daytime relief and at night try NyQuil for fast relief so you can rest
  • EFFECTIVE COLD & FLU SYMPTOM RELIEF: DayQuil and NyQuil Cold & Flu medicine temporarily relieve common cold & flu symptoms
  • FEEL BETTER FAST: Just one dose starts working fast to provide effective cold & flu relief
  • POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS: Life doesn’t stop when you have a cold, DayQuil and NyQuil relieve bothersome symptoms, such as cough and fever, day and night
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND** Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
No. 8
Coricidin HBP Decongestant-Free Cough and Cold Medicine - Specially Designed Relief for High Blood Pressure, Cough, Runny Nose, Sneezing and Cold Symptoms (16 Count)
6,220 Consomer Reviews
Coricidin HBP Decongestant-Free Cough and Cold Medicine - Specially Designed Relief for High Blood Pressure, Cough, Runny Nose, Sneezing and Cold Symptoms (16 Count)
  • The no.1 brand that gives powerful cold symptom relief without raising your blood pressure
  • Provides fast, powerful cold relief for people with high blood pressure
  • Cold and cough medicine for adults that relieves cough, runny nose, and sneezing
  • Decongestant free, cough cold medicine
  • Cold medicine comes in tablet form
  • HSA/FSA Eligible -- Check your plan for coverage.
SaleNo. 9
Vicks DayQuil Cold & Flu Medicine, Non-Drowsy Powerful Multi-Symptom Daytime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Nasal Congestion, Sinus Pressure and Cough, 48 Liquicaps
  • NON-DROWSY, DAYTIME RELIEF. DayQuil Cold & Flu LiquiCaps help you get your power back so you can enjoy the day
  • POWERFUL 6-SYMPTOM RELIEF. Temporarily relieves common cold & flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
  • #1 PHARMACIST RECOMMENDED over-the-counter cold & cough medicine from Vicks, the world’s #1 selling cough & cold brand
  • MULTI-SYMPTOM RELIEF. DayQuil Cold & Flu contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
  • CONTAINS ACETAMINOPHEN: A pain reliever/fever reducer than can help soothe your sore throat
  • ACTIVE INGREDIENTS: Acetaminophen 325Mg, Dextromethorphan Hbr 10Mg, Phenylephrine HCl 5Mg; Do not refrigerate
  • Temporarily relieves common cold and flu symptoms including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains and fever.
  • Non-Drowsy.
  • When using DayQuil or NyQuil products, carefully read each label to ensure correct dosing. Use as directed. Keep out of reach of children.
No. 10
Coricidin HBP Maximum Strength Cold & Flu Day & Night Sugar-Free Liquid Twinpack, Decongestant-Free Cold Medicine for Adults with High Blood Pressure -12 Fl Oz (Pack of 2)
  • Two 12 fl ounce bottles of Coricidin HBP Cold & Flu Day & Night Liquid Medicine, Cold Medicine for Adults with High Blood Pressure
  • HBP ADULT COLD MEDICINE: Decongestant-free Coricidin cold & flu medicine relieves symptoms without elevating blood pressure
  • BODY ACHES AND PAIN RELIEF: Acetaminophen reduces fever and relieves pain, including sore throat, headaches and body aches
  • COUGH RELIEF: A cough suppressant and expectorant temporarily relieves coughs and loosens congestion
  • MAXIMUM STRENGTH RELIEF: Coricidin HBP cold, cough & flu maximum strength medicine provides fast relief of symptoms for up to 4 hours
  • HSA/FSA Eligible -- Check your plan for coverage.

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Last update on 2024-05-05 / Affiliate links / Images from Amazon Product Advertising API