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The Best Cough & Sore Throat Medicine

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Discover now our comparison of the best Cough & Sore Throat Medicine. It is never easy to choose from the wide range of offers. On the market, you will find an incalculable number of models, all at different prices. And as you will discover, the best Cough & Sore Throat Medicine are not always the ones at the highest prices! Many criteria are used, and they make the richness and relevance of this comparison.
To help you make the best choice among the hundreds of products available, we have decided to offer you a comparison of the Cough & Sore Throat Medicine in order to find the best quality/price ratio. In this ranking, you will find products listed according to their price, but also their characteristics and the opinions of other customers. Also discover our comparisons by categories. You won’t have to choose your products at random anymore.

SaleNo. 1
In Each Liquid Gel: Active Ingredients: Acetaminophen (325 mg), Pain Reliever/Fever Reducer; Dextromethorphan HBr (10 mg), Cough Suppressant; Guaifenesin (200 mg), Expectorant; Phenylephrine HCI (5 mg), Nasal Decongestant. Inactive Ingredients: FD&C Yellow 6, Gelatin, Glycerin, Lecithin (Soy), Mineral Oil, Polyethylene Glycol, Povidone, Propylene Glycol, Shellac, Sorbitol Sorbitan Solution, Titanium Dioxide, Water.
  • MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Cold, Flu & Sore Throat helps reduce fever, relieve cough, sore throat, stuffy nose, chest & nasal congestion, headache and minor aches and pains
  • #1 TRUSTED COUGH & COLD: #1 Cough & Cold Brand Doctors Trust* and #1 Pharmacist Recommended Brand
  • PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain
  • COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough
  • EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion
  • NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure
  • USAGE: Use as directed; For ages 12+ years
SaleNo. 2
Mucinex Instasoothe Sore Throat Relief, Sore Throat Lozenges, Sore Throat Medicine with Hexylresorcinol, Cough Drops Alternative, 40 Elderberry & Wild Cherry Medicated Numbing Throat Drops
  • MUCINEX SORE THROAT RELIEF: These cough drops alternatives provide maximum strength pain relief* and temporarily relieves occasional minor irritation and pain associated with sore throat, sore mouth, and canker sores
  • FAST ACTING SORE THROAT LOZENGES: Mucinex Instasoothe Sore Throat Drops provide rapid relief that lasts & lasts
  • ELDERBERRY & WILD CHERRY FLAVOR SORE THROAT DROPS: These sore throat medicated drops are powered by a unique formula containing Hexlyresorcinol, not menthol like most cough drops
  • ON-THE-GO SORE THROAT RELIEF: Each Mucinex sore throat drop is individually wrapped & sealed for your convenience, so you don't have to worry about them unwrapping & sticking in your pocket or bag
  • BE PREPARED FOR COLD & FLU SEASON: Mucinex has a wide range of cough, cold and flu health care products to help your family get through cold & flu season, such as cough drops, sore throat spray, cold medicine, and cough medicine
  • TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust** and is also the #1 Pharmacist Recommended Brand*** so you can feel confident choosing Mucinex this cold & flu season
  • FSA & HSA Eligible: Save Up to 30%. Cover out-of-pocket expenses with pre-tax dollars; Product eligibility may vary by plan, check with your benefits administrator to determine which expenses are eligible before you shop
  • Based on amount of hexylresorcinol per adult dose; **IQVIA using ProVoice Survey, December 2022 ***U.S. News & World Report/Pharmacy Times 2023-2024
SaleNo. 3
Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct
  • 24-count combo pack, 16 day & 8 night caplets, of Extra Strength Tylenol Severe Cough + Sore Throat Day & Night caplets with acetaminophen & dextromethorphan HBr for powerful, multi-symptom relief for your painful sore throat & cough all day & night
  • Extra strength pain reliever & fever reducer + cough suppressant caplets help temporarily relieve your daytime or nighttime cold symptoms like head & body aches, fever & sore throat, & painful coughs, plus, relief from your runny nose at night
  • The maximum-strength, multi-symptom cold & flu medicine is formulated with 500 mg of extra strength acetaminophen to help relieve aches & pains & reduce fever, plus, 15 mg of dextromethorphan HBr cough suppressant to help calm your severe cough
  • Say goodnight to your cough & sore throat. The nighttime cold medicine also contains chlorpheniramine maleate, a powerful antihistamine to help relieve your runny nose. Available over the counter, keep this combo pack with your sick care supplies
  • Get fast, multi-symptom cold and flu relief with the power of extra strength acetaminophen from Tylenol, the #1 doctor recommended pain relief brand. For adults & children 12 years and older, take two caplets every six hours while symptoms last
No. 4
Tylenol Extra Strength Severe Cough + Sore Throat Nighttime Liquid Cold Medicine, Multi-Symptom Cold Relief, Acetaminophen Pain Reliever, Dextromethorphan HBr, Doxylamine Succinate, 8 Oz.
  • 8-fluid ounce bottle of Tylenol Extra Strength Severe Cough + Sore Throat Nighttime Liquid Cold Medicine with acetaminophen for multi-symptom cold & flu, cough & sore throat relief
  • The extra strength nighttime relief liquid is formulated to temporarily reduce fevers & relieve common cold or flu symptoms such as minor body aches & pains, headache, sore throat & cough
  • Each dose of Tylenol Extra Strength Nighttime liquid contains 1,000 mg of acetaminophen, a pain reliever & fever reducer, 30 mg of dextromethorphan HBr, a cough suppressant, as well as 12.5 mg of doxylamine succinate, an antihistamine
  • Take 30 mL of Tylenol Extra Strength liquid in the dosing cup provided every 6 hours while symptoms last. Do not take more than 90 mL in 24 hours, unless directed by a doctor
  • From the #1 doctor recommended pain relief brand, Tylenol Extra Strength Severe Cough + Sore Throat Nighttime liquid cold medicine can be used by adults & children 12 years & older for cough & sore throat relief at night
SaleNo. 5
Robitussin Adult Maximum Strength Cough + Chest Congestion DM Max (8 fl. oz. Bottle), Cough Suppressant & Expectorant, Raspberry Flavor
  • Maximum-strength formula with expectorant that thins and loosens mucus for productive coughs
  • Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
  • Suitable for adults and children 12 years and over
No. 6
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
  • 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
No. 7
Amazon Basic Care Tussin Severe CF Max Syrup, Multi-Symptom Cough, Cold and Flu Liquid Medicine, Non-Drowsy, Relieves Cough, Sore Throat, Body Aches, Fever, Nasal and Chest Congestion, 8 fl oz
  • ACTIVE INGREDIENTS: This cold medicine contains a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant. Compare to the active ingredients in Robitussin Severe Multi-Symptom Cough Cold + Flu.
  • MAXIMUM STRENGTH: This cold medicine provides maximum strength relief of multiple cold and flu symptoms such as cough, nasal congestion, sinus congestion and pressure, minor aches and pains, sore throat, headache and temporarily reduces fever.
  • MUCUS RELIEF: Take this cold medicine to help loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive.
  • NON-DROWSY: This non-drowsy cold and flu medicine provides relief for adults and children age 12 years and over. Dosage cup included.
  • GREAT TASTING COLD MEDICINE: Amazon Basic Care Tussin CF Max, Multiple Symptom Cough Cold & Flu is gluten free, sugar free and alcohol free. Maximum strength claim based on maximum levels of active ingredients per 4 hour dose.
No. 8
VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, RelievesHeadache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz
  • GREAT-TASTING HONEY FLAVORED DAYQUIL AND NYQUIL: Get the same cold & flu relief you expect from DayQuil & NyQuil SEVERE in a great-tasting honey-licious flavor
  • POWERFUL, MAXIMUM STRENGTH 9-SYMPTOM RELIEF DAY AND NIGHT: Use non-drowsy DayQuil SEVERE Honey for daytime and at night try NyQuil SEVERE Honey for fast relief so you can rest
  • POWERFUL COLD & FLU RELIEF: DayQuil and NyQuil SEVERE Honey formulas are flavored with real honey & temporarily relieve common cold & flu symptoms
  • PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS: Life doesn't stop when you have a cold; NyQuil and DayQuil SEVERE Honey tackle your most bothersome cold & flu symptoms
  • WORLD'S TOP SELLING OTC COUGH AND COLD BRAND: Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
SaleNo. 9
Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz
  • COUGH COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast-Max Cold & Flu and Nightshift Severe Cold & Flu provides powerful multi-symptom cold and flu relief for your worst cold and flu symptoms
  • SORE THROAT RELIEF: Both liquids contain Acetaminophen, which helps reduce fever and relieves sore throat, headache, and body pain
  • COUGH MEDICINE FOR ADULTS: Both liquids contain Dextromethorphan HBr, which helps suppress and quiet cough
  • CHEST CONGESTION RELIEF: Daytime liquid contains Guaifenesin, an expectorant, which helps relieve chest congestion and thins and loosens mucus
  • NASAL DECONGESTANT: Both liquids contain Phenylephrine HCl, a nasal decongestant, which helps relieve stuffy nose, sinus pressure, & nasal congestion
  • NIGHTTIME COLD AND FLU MEDICINE FOR ADULTS: Nighttime liquid contains Triprolidine HCl, an antihistamine, which helps relieve runny nose & sneezing
  • TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust(1) and is also the #1 Pharmacist Recommended OTC Expectorant(2); Get the brand that doctors trust and recommend
  • USAGE: Use as directed; For ages 12+ years
  • FSA & HSA Eligible: Save Up to 30%; Cover out-of-pocket expenses with pre-tax dollars (Product eligibility may vary by plan. Check with your benefits administrator to determine which expenses are eligible before you shop)
  • (1)IQVIA using ProVoice Survey, August 2023; (2)U.S. News & World Report/Pharmacy Times 2023-2024
No. 10
Propolis Throat Spray by Beekeeper's Naturals - 95% Bee Propolis Extract, Natural Immune Support & Sore Throat Relief - Antioxidants, Keto, Paleo, Gluten-Free (1.06 oz)(Pack of 1)
  • PROPOLIS IS THE DEFENDER OF THE HIVE. Bees use it to line the walls and keep germs out. We use it to support our immune systems, soothe dry, scratchy throats, combat free radical damage in the body, and feed the good bacteria in our gut.
  • IMMUNE SUPPORT: Propolis delivers over 300 other beneficial compounds, antioxidants, like flavanoids & polyphenols, that fight free radicals and combat oxidative stress. Our propolis is third-party tested to ensure it is pesticide-free.
  • BENEFITS: Immune Support, Soothe Scratchy & Dry Throat, Natural Remedy, Alcohol-Free, No Refined Sugars, Certified Keto, Sustainably Sourced, Certified Paleo, Third-party lab tested to ensure our products never contain pesticide residue or chemicals.
  • HOW WE SOURCE: We never overharvest from our hives and always ensure that our green apiaries are remote and far from harmful chemicals.
  • CLEAN INGREDIENTS: High-grade bee propolis extract, honey, non-GMO vegetable glycerin, and purified water. DOES NOT CONTAIN: artificial preservatives, colors, gluten, refined sugar, dairy, wheat, yeast, corn or soya. People allergic to bees, bee products, poplar tree products or balsam of Peru may experience allergic reactions.
  • At Beekeeper's Naturals we continually strive to source the highest quality ingredients from the hive. We recently switched to a new apiary partner for our propolis. The new propolis contains a higher concentration of bioactive polyphenols and flavonoids, which results in increased immune supporting properties per serving. With this stronger formula, you may notice a slight difference in taste, reminiscent of a honey cinnamon flavor, and a lighter color.

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Last update on 2025-04-13 / Affiliate links / Images from Amazon Product Advertising API