Addressing joint and muscle discomfort in cats is crucial for maintaining their mobility and overall quality of life. As cats age or face certain health conditions, these issues can significantly impact their activity levels and happiness. Selecting the appropriate medication can provide much-needed relief, allowing your feline companion to move more freely and comfortably.
- Drug free: Proactive Support from Tylenol with turmeric contains no drugs, acetaminophen, or other pain relievers and offers joint and muscle support from a trusted brand and decades of experience
- Advanced formula: Science-backed TamaFlex blend of turmeric and tamarind extracts helps with inflammation support; includes cucumber extract, shown to be better at supporting joint comfort than glucosamine chondroitin
- Clinically shown: Demonstrated in 2 trials to support joint comfort and flexibility in 5 days, improvements reported at day 5 that continued throughout studies; a great choice in joint supplements for women and men
- Turmeric supplement: Each 30-count bottle provides a one-month supply; for adults 18+ who should take one caplet per day; consistency helps maintain joint comfort and flexibility over time
- From a trusted brand: Developed with doctors; this drug-free option is made with science backed ingredients; the brand so many have trusted for decades – Tylenol
- Fast, strong pain relief: Tylenol acetaminophen 650mg extended-release caplets; unique bi-layer design delivers fast, strong relief that lasts up to 8 hours; won’t irritate your stomach the way ibuprofen can
- Minor arthritis pain reliever: #1 Doctor Recommended OTC brand for arthritis pain*; as a sponsor of the National Arthritis Foundation Tylenol takes your pain seriously; with fast-acting, long lasting pain relief *Based on a Survey of Doctors (IQVIA 2025)
- Muscle aches and pain relief: Tylenol pain relief caplets can help with muscular aches, headaches, premenstrual and menstrual cramps, toothaches; and pain symptoms from the common cold
- Minor joint pain relief: Rapid, sustained relief for the joints in your hands, wrists, knees, ankles, elbows, and feet
- Does not contain aspirin or ibuprofen: Tylenol arthritis caplets contain 650 mg of acetaminophen — a powerful option to consider. Extended relief pain management; FSA/HSA eligible without a prescription. Check your plan for details as plans may vary
- MAXIMUM OTC STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
- FAST-ACTING OTC LIDOCAINE — Containing 4% lidocaine, this liquid works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
- ROLLER BALL STYLE APPLICATION — Hands-free easy application keeps hands clean and dry; secure screw cap for convenient use on the go
- NON-GREASY FORMULA — Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
- TIPS FOR SUCCESSFUL USE — Lightly shake then flip the bottle upside down and glide over the skin, allowing the product to fully lubricate the rollerball while applying a thin, even layer of the product
- SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
- Compare to Aspercreme Lidocaine Pain Relief Liquid active ingredients
- 2.5 oz. roll-on application bottle (73 mL)
- 2-Ounce Trial Size – Support Everyday Movement with Penetrex Joint & Muscle Care Intensive Concentrate Cream. Designed to help soothe with a lightweight formula that absorbs quickly and leaves you feeling refreshed.
- Refreshing Experience: Our luxuriously smooth cream provides a refreshing sensation that helps calm after activity, long days, or exercise.
- Thoughtfully Selected Ingredients: Formulated with arnica, MSM, vitamin B6 and botanical extracts chosen to support a calming and comfortable experience.
- Perfect for Active Lifestyles: Use before or after workouts, outdoor activities, travel, or long days on your feet as part of your daily comfort routine.
- Clean Feel and Scent: Our fast-absorbing cream glides on smoothly with no odor and no greasy residue.
- One 3.5 oz/100 g tube and one 0.71 oz/20 g travel size tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
- Number 1 Doctor Recommended topical pain relief brand
- Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
- An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
- Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain
- Significant Arthritis Pain Relief, within seven days of continuous use and long-lasting relief when applied four times a day; Apply on up to two joints at the same time for hand pain, wrist pain, elbow pain, ankle pain, foot pain or knee pain relief
- Paraben and Dye-Free, Voltaren diclofenac gel is a non-greasy and clean scented gel
- Voltaren Arthritis Pain Gel comes in a tube with flip cap and includes dosing card for proper dosage as well as a 20 g trial tube
- PAIN RELIEVING PATCH: Effective for large pain areas, these comfortable & convenient topical patches have 3 powerful pain fighters that work at the site of pain. Analgesics include camphor, menthol & methyl salicylate.
- VERSATILE COMFORT: With rounded corners & flexible fabric, application is easy & the patches bend with your movements. The patches stay where you need them & are easy to remove.
- TARGETED RELIEF: Provides temporary relief of pain associated with sore back, neck, wrist, ankle, hip, shoulder, knee & elbow. Help alleviate muscle soreness, backache, joint pain & sprains.
- LONG-LASTING: For penetrating, mess-free & targeted relief, apply spray or patch to manage pain in specific areas. Salonpas pain relieving patches & sprays offer pain relief for up to 8 hours.
- SOOTHE YOUR PAIN: With pain relief patches, sprays, creams, gels & liquids, Salonpas is here to help you get through your day with discreet, easy-to-use, topical pain relief for temporary relief of aches & pains.
- Lidocaine Pain Relief Roll-On: Helps provide temporary relief from nerve, joint, & muscle pain with targeted application
- 4% Lidocaine & Phenol Formula: Combines lidocaine & phenol to help numb pain & support comfort in affected areas
- Fast-Acting Topical Relief: Helps deliver quick relief from everyday aches & discomfort with a convenient roll-on format
- Non-Greasy, No-Mess Application: Lightweight formula dries quickly & applies easily without residue
- Daily Pain Relief Support: Can be used as directed to help manage ongoing discomfort & support mobility
- Muscle & Leg Cramp Relief: Clinically trusted Theraworx Muscle Cramps provide fast-acting relief for muscle cramps and spasms; made with magnesium sulfate* to help soothe tight, overworked muscles and to help support muscle recovery.
- Long-lasting relief: Theraworx penetrates deep to provide lasting relief with no-mess, no strong odor; use Theraworx before activity to help prepare muscles and after exercise to help relieve temporary muscle fatigue.
- Use for Major Muscle Groups: Helps prevent muscle cramps and helps ease post-cramp soreness; it is suitable for use on major muscle groups, including the legs, calves, feet, back, neck, and hands.
- Daily relief that fits your routine: Whether you're at work, recovering after activity or settling in for the night at home, this easy, no-touch roll-on absorbs quickly into the skin & is safe to use daily; it’s TSA friendly for your travels too.
- Made with natural Ingredients: Paraben free and made with Vitamin E and aloe, it also helps moisturize and soothe the skin; FSA/HSA eligible.
- ARNICA: This homeopathic medicine helps temporarily discomfort.
- Fast-Absorbing Topical Gel
- Plant-Based Active Ingredient
- Gentle, Homeopathic Approach
- Trusted Since 1932 - From Boiron, a global leader in homeopathic medicine. Our mission is to provide quality remedies that help you feel your best — with a satisfaction promise backed by decades of expertise.
- XL BENEFITS BEYOND OMEGA-3s – Backed by over 40 years of clinical research, this high-potency blend promotes joint, muscle, and respiratory health.* OmegaXL is the ultimate joint health and mobility support supplement that is over 16 times more potent...
- MUSSELS FOR YOUR JOINTS - Don’t let minor aches hold you back from living a healthy, active life. OmegaXL is a drug-free, natural dietary supplement that, when taken daily, has been shown to promote joint health and improve mobility. Our proprietary...
- MORE THAN A FISH OIL - OmegaXL contains the oil extract from green-lipped mussels that are exclusively sourced from and sustainably farmed in the pristine waters of New Zealand. Our one-of-a-kind proprietary formula is packed with a powerful combination...
- GET THE BENEFITS, WITHOUT THE FISHY AFTERTASTE - OmegaXL is provided in a convenient, small and easy-to-swallow soft gel with no fishy aftertaste or burps. This product is free of gluten, allergenic levels of shellfish protein, artificial ingredients...
- COMMITTED TO WELLNESS - Founded in 2003, Great HealthWorks is dedicated to delivering quality health and wellness products to our consumers. OmegaXL is produced using Current Good Manufacturing Practices (cGMPs) set forth by the FDA. All active...
This article is part of our complete guide Cat Supplies — browse all our comparisons and buying guides.
Last update on 2026-09-01 / Affiliate links / Images from Amazon Product Advertising API
How to Choose the Best Joint & Muscle Pain Relief Medications
Consult Your Veterinarian First
The most critical step before administering any pain relief medication to your cat is to consult with a veterinarian. They can accurately diagnose the cause of your cat's pain, which is essential for effective treatment. Different types of pain require different approaches, and a vet can recommend the safest and most appropriate options for your specific pet's needs and health history.
Understand Active Ingredients and Formulations
- Active Ingredients: Discuss with your vet which active ingredients are suitable for cats. Some human medications are highly toxic to felines. Veterinarian-approved options often include non-steroidal anti-inflammatory drugs (NSAIDs) specifically formulated for cats, or other natural supplements.
- Formulations: Pain relief medications come in various forms, such as oral liquids, chewable tablets, or injections. Consider which formulation will be easiest for you to administer to your cat and which your cat is most likely to accept.
Consider Potential Side Effects and Interactions
All medications carry a risk of side effects. Your veterinarian will discuss potential side effects associated with recommended treatments and how to monitor for them. It's also vital to inform your vet about any other medications or supplements your cat is currently taking to avoid dangerous interactions. Proper dosage and administration are key to minimizing risks.