Stationery & Supplies

The Best Paper Facial Tissues

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Our picks are based on Amazon bestseller rankings, verified customer ratings, and product availability. We update our recommendations regularly to ensure accuracy.

Facial tissues are a daily essential, offering comfort and convenience for everything from allergies to spills. Choosing the right tissues can significantly impact your comfort and the overall experience, especially in an office or school setting. Consider factors like softness, absorbency, and strength to ensure you get the best value and performance.

No. 1
Amazon Basics Facial Tissue, 2-Ply, 640 Count (4 Packs of 160), (Packaging may vary)
  • SHIPMENT CONTAINS: 4 tissue boxes with 160 tissues per box (640 tissues total), perfect for bathrooms, living rooms, bedrooms, offices, and classrooms
  • SOFT AND STRONG: 2-ply facial tissues designed with two strong layers for ultimate care and comfort during everyday use
  • STYLISH DESIGN: Cube color combinations may vary, offering a clean look that complements any room decor
  • FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
  • SUSTAINABILITY CERTIFIED: FSC-certified facial tissue made with materials from well-managed forests, recycled materials, and other controlled wood sources
  • PACKAGING MAY VARY: Packaging may be different than what is shown but item and quality remain the same
No. 2
Amazon Basics Facial Tissues with Lotion, 2-Ply, 300 Count (4 Boxes, 75 Tissues per Box), Packaging May Vary
  • Packaging may vary
  • IN THE BOX: 4 cube boxes; 75 tissues per cube (300 tissues total)
  • SOFT AND GENTLE: 2-ply white facial tissues infused with lotion for extra comfort
  • FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
  • USE ANYWHERE: perfect for bathrooms, living rooms, bedrooms, offices, classrooms
  • STYLISH VARIETY: Cube color combinations may vary
No. 3
Amazon Brand - Presto! Ultra-Soft 3-Ply Premium Facial Tissues, 264 Count (4 Cube Boxes of 66), Packaging May...
  • Packaging may vary
  • IN THE BOX: 4 Cube Boxes of facial tissues with 66 3-ply tissues in each box
  • ULTRA SOFT: Premium facial tissues offer durable strength and ultra softness
  • FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
  • FUN & COLORFUL: Eye-catching colors and designs; cube box color combinations may vary
  • USE ANYWHERE: Ideal for bathrooms, living rooms, bedrooms, offices, classrooms and more
No. 4
Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box, 3-Ply, Packaging May Vary
  • WHAT'S INCLUDED — 8 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 80 tissues per box (640 tissues total)
  • FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
  • SILKY SOFTNESS — These facial tissues are made with 3 layers and are silky soft for up to 100% irritation-free skin for an extra bit of comfort when you need it
  • ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)
No. 5
Kleenex Trusted Care Facial Tissues, 8 Flat Boxes, 200 Tissues per Box, 2-Ply, Packaging May Vary
  • WHAT'S INCLUDED — 8 flat boxes of Kleenex Trusted Care Facial Tissues, 2-Ply, 200 tissues per box (1,600 tissues total)
  • THE ORIGINAL SOFT & STRONG TISSUE — These facial tissues are made with same the trusted softness and strength that Kleenex is known for
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • FOR EVERYDAY USE — Kleenex is perfect to use during allergy season, back-to-school season, and cold and flu season
  • 2 LAYERS, 2 BENEFITS — Our facial tissues are thick, absorbent, and made with 2 strong layers to help keep hands clean
  • PERFECT FOR ANY HOME — Our Kleenex tissues boxes come in various stylish designs that complement your home décor (packaging may vary)
SaleNo. 6
Kleenex Ultra Soft Facial Tissues, 4 Cube Boxes, 60 Tissues per Box, 3-Ply (240 Total), Packaging May Vary
  • WHAT'S INCLUDED — 4 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 60 tissues per box (240 tissues total)
  • ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
  • TAKE ON ALLERGY SEASON — Whether you’re facing runny noses or watery eyes this allergy season, Kleenex Ultra Soft is there for it all
  • SILKY SOFTNESS — These facial tissues are made with 3 layers and are silky soft for up to 100% irritation-free skin for an extra bit of comfort when you need it
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)
No. 7
Puffs Facial Tissues Ultra Soft, 4 Family Boxes, 124 Facial Tissues per Box, Allergies and Colds (Packaging...
  • Pack includes 4 Family Boxes (124 Tissues Per Box) of Puffs Ultra Soft Facial Tissues
  • Perfect size to stash anywhere
  • Gentle on sensitive skin
  • Made with cushiony thickness
  • Comforts needy noses
No. 8
Amazon Basics Facial Tissue, 2-Ply, Soft and Strong, 2880 Count (18 Packs of 160), (Packaging May Vary)
  • Packaging may vary
  • IN THE BOX: 18 tissue boxes; 160 tissues per box (2,880 tissues total)
  • SOFT AND STRONG: 2-ply facial tissues designed with two strong layers for ultimate care and comfort
  • FSC-CERTIFIED SKIN FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
  • USE ANYWHERE: perfect for bathrooms, living rooms, bedrooms, offices, classrooms
  • STYLISH VARIETY: Cube color combinations may vary
No. 10
Kleenex Ultra Soft Facial Tissues, 3 Flat Boxes, 120 Tissues per Box, 3-Ply (360 Total), Packaging May Vary
  • WHAT'S INCLUDED — 3 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 120 tissues per box (360 tissues total)
  • ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
  • TAKE ON ALLERGY SEASON — Whether you’re facing runny noses or watery eyes this allergy season, Kleenex Ultra Soft is there for it all
  • SILKY SOFTNESS — These facial tissues are made with 3 layers and are silky soft for up to 100% irritation-free skin for an extra bit of comfort when you need it
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

Last update on 2026-07-09 / Affiliate links / Images from Amazon Product Advertising API

How to Choose the Best Paper Facial Tissues

Key Features to Consider

  • Softness: Look for tissues made from high-quality, soft fibers. Many brands offer lotion-infused or triple-ply options for enhanced gentleness, which is crucial for frequent use or sensitive skin.
  • Absorbency and Strength: Tissues should be absorbent enough to handle sneezes and minor spills without falling apart. Stronger tissues are less likely to tear during use, providing a more reliable experience.
  • Puff Count and Size: Consider the number of tissues per box and their individual size. Higher puff counts mean fewer box changes, while larger tissues can be more effective.
  • Hypoallergenic and Fragrance-Free Options: If you or others in your household have allergies or sensitivities, opt for hypoallergenic and fragrance-free varieties to minimize irritation.

Environmental Considerations

  • Recycled Content: Many manufacturers now offer tissues made with recycled materials, appealing to environmentally conscious consumers. Check packaging for details on post-consumer recycled content.
  • Sustainable Sourcing: Look for brands that emphasize sustainable forestry practices, such as those certified by organizations like the Forest Stewardship Council (FSC).

Packaging and Dispensing

  • Box Design: While functionality is key, the aesthetic of the box might matter in certain settings. Some brands offer decorative boxes suitable for display.
  • Ease of Dispensing: Ensure the tissues pull out easily one at a time without snagging or tearing prematurely within the box.

Frequently Asked Questions

What makes facial tissues hypoallergenic?
Hypoallergenic tissues are formulated to be less likely to cause allergic reactions. They typically do not contain harsh chemicals, dyes, or fragrances that can irritate sensitive skin or trigger allergies.
Are triple-ply tissues always better than double-ply?
Triple-ply tissues generally offer superior softness and strength compared to double-ply. However, the quality of the plies themselves can vary by brand, so softness and strength are not solely determined by the ply count.
How can I tell if tissues are environmentally friendly?
Look for certifications like FSC (Forest Stewardship Council) on the packaging, which indicates responsible forest management. Tissues made with a high percentage of post-consumer recycled content are also a more sustainable choice.
What is the benefit of lotion-infused tissues?
Lotion-infused tissues contain emollients like aloe or vitamin E, which help to moisturize and protect the skin. This can be particularly beneficial for individuals who experience dryness or irritation from frequent blowing.
Are fragrance-free tissues better for sensitive noses?
Yes, fragrance-free tissues are ideal for individuals with sensitivities to scents, as they eliminate a common source of irritation. This ensures a more comfortable experience, especially during allergy season.