Beauty & Grooming

The Best Toothpaste

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Our picks are based on Amazon bestseller rankings, verified customer ratings, and product availability. We update our recommendations regularly to ensure accuracy.

Selecting the right toothpaste is crucial for maintaining optimal oral hygiene and preventing common dental issues. With a vast array of options available, understanding key features and benefits can help you make an informed decision that suits your specific needs.

SaleNo. 1
Crest + Scope Whitening Toothpaste - Pack of 3, 5.4 Oz Tubes - Anticavity Fluoride Toothpaste, Fresh Breath...
  • BULK TOOTHPASTE: Includes three 5.4 oz cartons of Crest + Scope Whitening Toothpaste.
  • BAD BREATH KILLER: Our Crest toothpaste kills millions of bad breath germs in laboratory tests, ensuring your oral hygiene.
  • CAVITY AND TARTAR FIGHTER: Fights cavities and tartar, strengthening enamel with our fluoride toothpaste.
  • WHITENING TOOTHPASTE: Gently removes surface stains for whiter teeth, making it an excellent choice for enamel safe whitening.
SaleNo. 2
Colgate Optic White Advanced Hydrogen Peroxide Toothpaste, 3 Pack, 3.2 oz
  • WHAT’S INCLUDED: Three 3.2 OZ tubes of Colgate Optic White Advanced Sparkling White Toothpaste
  • DEEP STAIN REMOVAL: Advanced Sparkling White Toothpaste removes 5 years of deep-set stains* *When brushing twice daily for 2 weeks
  • 2% HYDROGEN PEROXIDE: Our proprietary formula with HP Complex is powered by hydrogen peroxide—the same whitening ingredient used by dentists—to deeply whiten beyond surface stains
  • ENAMEL SAFE: The triple toothpaste pack uses a clinically proven whitening formula that works without harming enamel and is safe for daily use
  • RAPID WHITENING: Starts whitening after the first brush
No. 3
Crest 3D White Advanced, Teeth Whitening Toothpaste for Adults, 3.7 oz, 4 Pack, Cavity Protection Fluoride...
  • Remove Surface Stains: Crest 3D White Brilliance Toothpaste removes 90% more surface stains vs. regular toothpaste, enhancing your daily brushing routine and preventing future stains
  • This deep stain remover effectively delivers whitening tooth paste benefits, ensuring a visibly brighter smile.This toothpaste with fluoride helps fight against cavities as well
  • Whitening Benefits: Get whiter teeth in 5 days, promoting white teeth and enhancing your oral hygiene routine. Available to purchase as bulk toothpaste pack of 4, this pack-size is an integral component of your household essentials
  • This tooth whitening toothpaste is an effective teeth whitener and offers enamel repair toothpaste properties. A single pack of this product is suitable as a travel tooth paste, making it a perfect add to your mini travel essentials kit
  • Crest 3D White Toothpaste: You will receive 4 x 3.7 oz tubes of Crest 3D White Advanced Luminous Mint Toothpaste, a part of your essential oral care routine
No. 4
Sensodyne Repair and Protect Whitening Toothpaste, 3.4 oz (Pack of 2)
  • Two 3.4-ounce tubes of Sensodyne Repair and Protect Teeth Whitening Toothpaste
  • Toothpaste for sensitive teeth from the number one dentist recommended brand for sensitive teeth
  • Sensodyne fluoride toothpaste builds a repairing layer inside the tiny tubules of the sensitive areas of your teeth (2, 3)
  • Stannous fluoride formula provides lasting protection against sensitivity with twice daily brushing so you can enjoy life without the worry of sensitivity (1)
  • Toothpaste with an ingredient that is clinically proven for sensitivity relief and lasting protection (1)
  • This toothpaste repairs sensitive areas of your teeth so you can go back to the things that you enjoy eating the most (2, 3)
  • Sensitivity-friendly flavor with a gentle, clean taste; this whitening toothpaste is breath freshening
  • Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
No. 5
Colgate Cavity Protection Fluoride Toothpaste, Mint, 6 Pack, 6 oz
  • WHAT’S INCLUDED: Six (6) 6.0 oz tubes of Colgate Cavity Protection Fluoride Toothpaste in Great Regular Mint Flavor
  • FIGHTS CAVITIES: This anticavity fluoride toothpaste pack helps prevent cavities and provides effective daily cavity protection when used daily to brush your teeth; use this bulk toothpaste pack to stock up on extras for your home, family, or bathroom
  • STRENGTHENS TEETH ENAMEL: Colgate Cavity Protection Toothpaste is an enamel strengthening toothpaste and is formulated with active fluoride to help strengthen teeth enamel
  • FRESHENS BREATH: These mint toothpastes feature a refreshing Great Regular Mint Flavor to help freshen breath and leave your mouth clean
  • ADA ACCEPTED: Colgate Cavity Protection Toothpaste has been independently tested and reviewed by the American Dental Association to be safe and effective for daily use; it’s also a gluten free toothpaste and can be used to brush your teeth twice daily
SaleNo. 6
Colgate MaxFresh Fluoride Toothpaste, Clean Mint, 4 Pack, 6.3 oz
  • Includes four 6.3 oz tube of Colgate MaxFresh Clean Mint Toothpaste
  • Powered by Ultrafreeze, Colgate MaxFresh Toothpaste offers 10X longer-lasting cool for fresh breath*
  • Fluoride toothpaste formula helps fight cavities
  • This spearmint toothpaste, with hundreds of mini breath strips, unleashes a powerful rush of freshness for long-lasting fresh breath
  • Release an instant blast of freshness with Colgate MaxFresh Clean Mint Toothpaste
No. 7
Baking Soda & Peroxide Whitening Toothpaste, Fresh Mint, 5.7 oz, Pack of 2
  • Contains baking soda and peroxide for a clean mouth feeling
  • Whitens teeth by removing surface stains
  • Gentle on tooth enamel
  • Freshens breath for a clean feeling mouth
  • For better whitening, use with Oral-B iO brush, Crest 3DW mouthwash, and Crest 3DWhitestrips
  • Brush 2X per day for 2 minutes
SaleNo. 8
Crest 3D White Advanced Teeth Whitening Toothpaste, Radiant Mint, 3.3 oz, Pack of 2
  • You will receive two (2) 3.3 oz tubes of Crest 3D White Advanced Radiant Mint Toothpaste
  • Removes 90% more surface stains* *Vs. regular toothpaste
  • 2X faster whitening
  • Get brighter teeth with 3DW unique technology
  • Gives you a flawless bright and white smile
No. 9
Aquafresh Cavity Protection Fluoride Toothpaste, 5.6 oz
  • Contains one 5.6oz tube in the pack
  • Cool mint flavor refreshes your breath
  • Triple protection toothpaste prevents cavities, maintains strong teeth, and healthy gums
  • Strengthens enamel to provide effective protection
  • Helps protect teeth from sugar acids
  • Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
SaleNo. 10
Colgate Total Whitening Toothpaste Paste, 5.1 oz, 2 Pack, Fluoride Antibacterial for Plaque, Gingivitis...
  • WHAT’s INCLUDED: Includes two 5.1 oz tubes of Colgate Total Whitening Toothpaste, Paste, Mint Flavored
  • BE DENTIST READY: Helps stop oral care problems like gingivitis and cavities before they start
  • ROOT CAUSE PROTECTION: Clinically proven to target the root cause of common oral health issues**
  • 24 HOUR ANTIBACTERIAL TOOTHPASTE: Provides 24 hour antibacterial protection with twice daily brushing***
  • FIGHTS MULTIPLE ISSUES: Fights root cause**** of gingivitis, plaque, tartar, cavities, sensitivity, bad breath, enamel erosion, stains

Last update on 2026-09-06 / Affiliate links / Images from Amazon Product Advertising API

How to Choose the Best Toothpaste

Key Ingredients to Look For

When choosing a toothpaste, several key ingredients play vital roles in promoting oral health. Fluoride is paramount, as it strengthens tooth enamel and helps prevent cavities by remineralizing tooth surfaces. Look for toothpastes containing sodium fluoride, stannous fluoride, or sodium monofluorophosphate. For those with sensitive teeth, ingredients like potassium nitrate or strontium chloride can help block pain signals. Whitening toothpastes often include mild abrasives like hydrated silica or calcium carbonate to gently remove surface stains, while others may use chemical agents like hydrogen peroxide for a more pronounced whitening effect.

Addressing Specific Dental Concerns

Toothpastes are formulated to address a variety of oral health concerns. Cavity protection is a primary function, with most toothpastes containing fluoride to combat tooth decay. For individuals prone to gum disease or gingivitis, look for formulations with antibacterial agents like triclosan (though less common now) or zinc citrate. Tartar control toothpastes typically contain pyrophosphates or zinc citrate to help prevent the buildup of plaque into hardened tartar. If you experience persistent bad breath, consider toothpastes with specialized odor-neutralizing ingredients or those designed to combat dry mouth, which can be a contributing factor.

Choosing the Right Formulation for You

Beyond active ingredients, consider the texture and flavor of the toothpaste. Options range from pastes and gels to powders. Gels often have a smoother feel, while pastes can offer a more traditional experience. Flavor is subjective, with mint being the most common, but fruit and other flavors are available for those who prefer them. Some individuals may prefer toothpastes with natural ingredients or those free from artificial sweeteners, colors, or foaming agents like sodium lauryl sulfate (SLS), which can sometimes cause irritation.

Frequently Asked Questions

What is the most important ingredient in toothpaste?
Fluoride is considered the most important ingredient in toothpaste. It strengthens tooth enamel, making it more resistant to acid attacks from plaque bacteria and sugars, thereby preventing cavities.
How can I choose a toothpaste for sensitive teeth?
For sensitive teeth, look for toothpastes containing potassium nitrate or strontium chloride. These ingredients work by blocking the transmission of pain signals from the tooth's nerve to the surface.
Are whitening toothpastes effective and safe?
Whitening toothpastes can be effective at removing surface stains, often using mild abrasives or chemical agents. They are generally safe for daily use when used as directed, but some may cause temporary sensitivity.
What should I look for if I have gum problems?
If you experience gum issues like gingivitis, opt for toothpastes with antibacterial properties or those specifically designed for gum health. These formulations can help reduce plaque and inflammation along the gum line.
Is SLS (sodium lauryl sulfate) bad for toothpaste?
Sodium lauryl sulfate is a common foaming agent that can sometimes cause irritation or mouth sores in individuals with sensitivities. If you experience this, consider an SLS-free toothpaste.