The Best Cold & Flu Medicine

Looking for the best Cold & Flu Medicine?

Discover now our comparison of the best Cold & Flu Medicine. It is never easy to choose from the wide range of offers. On the market, you will find an incalculable number of models, all at different prices. And as you will discover, the best Cold & Flu Medicine are not always the ones at the highest prices! Many criteria are used, and they make the richness and relevance of this comparison.
To help you make the best choice among the hundreds of products available, we have decided to offer you a comparison of the Cold & Flu Medicine in order to find the best quality/price ratio. In this ranking, you will find products listed according to their price, but also their characteristics and the opinions of other customers. Also discover our comparisons by categories. You won’t have to choose your products at random anymore.

No. 1

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu
NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains
NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains
PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat
COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help

SaleNo. 2

Mucinex Fast-Max Liquid Gels for Day/Night Cold and Flu, 24 Count

MAXIMUM STRENGTH MUCINEX FAST-MAX COLD & FLU: Multi-Symptom Relief medicine; 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful medicine
DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day Time Cold and Flu helps reduce fever, relieve cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, minor aches and pains, headache and sore throat
NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Night Time Cold and Flu helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose and sore and itchy throat
# 1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand**
DAY TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever and Fever reducer; Dextromethorphan HBr - Cough Suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal Decongestant

SaleNo. 3

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. From the doctor recommended pain relief brand, the combo pack includes 16 Daytime and 8 Nighttime caplets for relief any time of the day
The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion and pressure
Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine.

SaleNo. 4

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu

No. 5

Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks NyQuil Cold & Flu
RELIEVES COLD & FLU SYMPTOMS: Amazon Basic Care Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose
NIGHTTIME COLD AND FLU RELIEF: Amazon Basic Care Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.
EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.
GLUTEN FREE: This product is Gluten Free. Contains 10% ALCOHOL.

No. 6

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.

SaleNo. 7

Boiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count

HOMEOPATHIC FLU RELIEF: Oscillococcinum works with your body to help temporarily relieve fatigue, headache, body aches, chills & fever. Safe for ages 2 & up, take at the first sign of flu-like symptoms.
HOLISTIC SUPPORT: Looking for homeopathic flu relief for the whole family? Oscillococcinum's sweet-tasting pellets dissolve quickly & easily under the tongue; no water, chewing, or swallowing required.
SHORTEN YOUR SYMPTOMS: Oscillo has been shown in clinical studies to help reduce both the duration & the severity of flu-like symptoms when taken at the onset. Non-drowsy, easy-to-take relief!
HOMEOPATHIC MEDICINE uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our tablets, pellets, & topical treatments work with your body without the risk of contraindications, or known drug interactions.
THE BOIRON PROMISE: We believe there’s more than one way to feel better. Since 1932, we have been committed to providing quality medicines. As a world leader in homeopathy, our passion is your health. Our promise is your satisfaction.

No. 8

Amazon Basic Care Daytime and Nighttime Max Strength Severe Cold and Flu Relief Medicine, Combo Pack, Liquid Medication for Day and Night, Original and Berry, 24 fl oz (Pack of 1)

ACTIVE INGREDIENTS: Compare this daytime and nighttime cold medicine to Vicks DayQuil Severe and Vicks NyQuil Severe active ingredients
DAYTIME RELIEF: Daytime Severe cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), guaifenesin (expectorant) and phenylephrine HCl (nasal decongestant) to help you power through the day
NIGHTTIME RELIEF: Nighttime Severe cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), doxylamine succinate (antihistamine) and phenylephrine HCl (nasal decongestant) so you can rest at night
AROUND THE CLOCK: Relieve symptoms during the day and at night while you sleep with Amazon Basic Care Daytime and Nighttime Severe Cold and Flu Relief
MAXIMUM STRENGTH: Get maximum strength relief for your severe cold and flu symptoms

No. 9

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

SaleNo. 10

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct

Twin 2 Pack of 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief

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We do everything we can to offer you relevant comparisons, based on various criteria and constantly updated. The product you are looking for is probably among these pages. A few clicks will allow you to make a fair and relevant choice. Don’t be disappointed with your purchases made on the Internet and compare the best Cold & Flu Medicine now!

Last update on 2025-06-07 / Affiliate links / Images from Amazon Product Advertising API

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