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The Best Cold & Flu Medicine

Looking for the best Cold & Flu Medicine?

Discover now our comparison of the best Cold & Flu Medicine. It is never easy to choose from the wide range of offers. On the market, you will find an incalculable number of models, all at different prices. And as you will discover, the best Cold & Flu Medicine are not always the ones at the highest prices! Many criteria are used, and they make the richness and relevance of this comparison.
To help you make the best choice among the hundreds of products available, we have decided to offer you a comparison of the Cold & Flu Medicine in order to find the best quality/price ratio. In this ranking, you will find products listed according to their price, but also their characteristics and the opinions of other customers. Also discover our comparisons by categories. You won’t have to choose your products at random anymore.

SaleNo. 1
Boiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count
  • HOMEOPATHIC FLU RELIEF: Oscillococcinum works with your body to help temporarily relieve fatigue, headache, body aches, chills & fever. Safe for ages 2 & up, take at the first sign of flu-like symptoms.
  • HOLISTIC SUPPORT: Looking for homeopathic flu relief for the whole family? Oscillococcinum's sweet-tasting pellets dissolve quickly & easily under the tongue; no water, chewing, or swallowing required.
  • SHORTEN YOUR SYMPTOMS: Oscillo has been shown in clinical studies to help reduce both the duration & the severity of flu-like symptoms when taken at the onset. Non-drowsy, easy-to-take relief!
  • HOMEOPATHIC MEDICINE uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our tablets, pellets, & topical treatments work with your body without the risk of contraindications, or known drug interactions.
  • THE BOIRON PROMISE: We believe there’s more than one way to feel better. Since 1932, we have been committed to providing quality medicines. As a world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
No. 2
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count
  • ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
  • EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
  • COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
  • COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
  • MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu
SaleNo. 3
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
  • RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
  • POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
  • NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
  • PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
No. 4
Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)
  • ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks NyQuil Cold & Flu
  • RELIEVES COLD & FLU SYMPTOMS: Amazon Basic Care Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose
  • NIGHTTIME COLD AND FLU RELIEF: Amazon Basic Care Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.
  • EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.
  • GLUTEN FREE: This product is Gluten Free. Contains 10% ALCOHOL.
SaleNo. 5
Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct
  • Twin 2 Pack of 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
No. 6
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
  • 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
SaleNo. 7
Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels
  • COUGH, COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast-Max Day Cold & Flu and Fast-Max Night Cold & Flu fast-dissolving liquid gels provides powerful multi-symptom relief for your worst cold and flu symptoms
  • SORE THROAT RELIEF: Both products contain Acetaminophen, which helps reduce fever and relieves sore throat, headache, and body pain
  • COUGH MEDICINE FOR ADULTS: Both products contain Dextromethorphan HBr, which helps suppress and quiet cough
  • CHEST CONGESTION RELIEF: Daytime cold medicine liquid gels contain Guaifenesin, an expectorant, which helps relieve chest congestion and thins and loosens mucus
  • NASAL DECONGESTANT: Both products contain Phenylephrine HCl, a nasal decongestant, which helps relieve stuffy nose, sinus pressure, & nasal congestion
  • NIGHTTIME COLD AND FLU MEDICINE FOR ADULTS: Nighttime liquid gels contain Doxylamine succinate, an antihistamine, which helps relieve runny nose & sneezing
  • TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend
  • FSA/HSA STORE ELIGIBLE MEDICATION: Save Up to 30%; Cover out-of-pocket expenses with pre-tax dollars (Product eligibility may vary by plan; Check with your benefits administrator to determine which expenses are eligible before you shop)
  • USAGE: Use as directed; For ages 12+ years
  • IQVIA using ProVoice Survey, August 2023; **U.S. News & World Report/Pharmacy Times 2023-2024
SaleNo. 8
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)
  • ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu
  • NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains
  • NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains
  • PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat
  • COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help
SaleNo. 9
Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz
  • COUGH COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast-Max Cold & Flu and Nightshift Severe Cold & Flu provides powerful multi-symptom cold and flu relief for your worst cold and flu symptoms
  • SORE THROAT RELIEF: Both liquids contain Acetaminophen, which helps reduce fever and relieves sore throat, headache, and body pain
  • COUGH MEDICINE FOR ADULTS: Both liquids contain Dextromethorphan HBr, which helps suppress and quiet cough
  • CHEST CONGESTION RELIEF: Daytime liquid contains Guaifenesin, an expectorant, which helps relieve chest congestion and thins and loosens mucus
  • NASAL DECONGESTANT: Both liquids contain Phenylephrine HCl, a nasal decongestant, which helps relieve stuffy nose, sinus pressure, & nasal congestion
  • NIGHTTIME COLD AND FLU MEDICINE FOR ADULTS: Nighttime liquid contains Triprolidine HCl, an antihistamine, which helps relieve runny nose & sneezing
  • TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust(1) and is also the #1 Pharmacist Recommended OTC Expectorant(2); Get the brand that doctors trust and recommend
  • USAGE: Use as directed; For ages 12+ years
  • FSA & HSA Eligible: Save Up to 30%; Cover out-of-pocket expenses with pre-tax dollars (Product eligibility may vary by plan. Check with your benefits administrator to determine which expenses are eligible before you shop)
  • (1)IQVIA using ProVoice Survey, August 2023; (2)U.S. News & World Report/Pharmacy Times 2023-2024
SaleNo. 10
Contac Non-Drowsy Day & Multi-Symptom Night Cold & Flu Medicine, Maximum Strength Relief for Fever, Sore Throat, Nasal Congestion, Head & Body Aches, Runny Nose, 28 Count, 16 Day, 12 Night Caplets
  • FAST-ACTING, MAXIMUM-STRENGTH RELIEF: Get 24-hour relief from common cold & flu symptoms, including nasal congestion, sinus congestion and pressure, sore throat, head & body aches and fever, runny nose, and sneezing
  • NON-DROWSY, DAYTIME RELIEF: Our severe cold & flu medicine provides symptom relief without making you drowsy; Stay alert and active throughout your day
  • NIGHTTIME COMFORT: Sleep better with our nighttime formula that eases symptoms for restful sleep
  • 24-HOUR RELIEF: Feel better and stay alert by using our daytime formula with Phenylephrine HCI a nasal decongestant to ease congestion and acetaminophen a pain reliever/fever reducer to relieve minor aches, pains and sore throat; get some rest at night with our nighttime formula that also contains Chlorpheniramine maleate an antihistamine to ease your symptoms overnight
  • FIGHT THE FLU & COLD: Contac Cold + Flu tackles severe cold & flu symptoms for adults and children 12 years and older; FSA/HSA eligible, gluten-free and no artificial colors
  • TRUSTED BRAND: Contac has been trusted to relieve cold and flu symptoms for over 55 years - Choose one of our formulations depending on your cold, flu or cough symptoms: Contac Cold + Flu Daytime for non-drowsy relief, Contac Cold + Flu Day & Night for 24-hour relief, Contac Cough & Congestion to thin and loosen mucus and control your cough for 12 hours, and Contac Chest Congestion to thin and loosen mucus and make coughs more productive

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Last update on 2025-03-06 / Affiliate links / Images from Amazon Product Advertising API