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The Best Non-aspirin Pain Relievers

Looking for the best Non-aspirin Pain Relievers?

Discover now our comparison of the best Non-aspirin Pain Relievers. It is never easy to choose from the wide range of offers. On the market, you will find an incalculable number of models, all at different prices. And as you will discover, the best Non-aspirin Pain Relievers are not always the ones at the highest prices! Many criteria are used, and they make the richness and relevance of this comparison.
To help you make the best choice among the hundreds of products available, we have decided to offer you a comparison of the Non-aspirin Pain Relievers in order to find the best quality/price ratio. In this ranking, you will find products listed according to their price, but also their characteristics and the opinions of other customers. Also discover our comparisons by categories. You won’t have to choose your products at random anymore.

No. 1
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)
  • ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol CapletsAmazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps also temporarily reduces fever
  • USE: Acetaminophen may be used as a pain reliever and fever reducer for adults and children 12 years and over
  • PAIN: Pain may begin with an injury or illness, but could also originate with anything from a bad mattress to arthritisACUTE PAIN: Acute pain acts as an alarm such as with a bee sting or stubbing your toe and can last for a few moments or for longer
  • Product may be manufactured in India or U.S.
No. 2
Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)
  • ACTIVE INGREDIENT: This product contains ibuprofen 200 mg, a pain reliever and fever reducer (NSAID); compare to the active ingredient in Advil Ibuprofen TabletsPAIN RELIEVER AND FEVER REDUCER: Proven pain relief without a prescription for tough pain such as muscular aches, minor arthritis pain, toothache, backache, menstrual cramps or minor aches and pains from the common cold; also temporarily reduces fever
  • STRONG RELIEF: Amazon Basic Care Ibuprofen Tablets 200 mg are strong on tough pain to help you get the relief you need to keep going; no prescription needed for this pain reliever and fever reducerEFFECTIVE: When pain tries to take over, turn to the proven pain relief of coated Amazon Basic Care Ibuprofen Tablets 200 mg; use for adults and children 12 years and over
  • IBUPROFEN is the number one doctor recommended back pain OTC active ingredient (of U.S. physicians surveyed by an independent market research firm)
  • Product may be manufactured in India or U.S.
SaleNo. 3
Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct
  • 100-count Tylenol Extra Strength Rapid Release Gels pain relief medicine with acetaminophen work fast to temporarily relieve minor aches and pains, headaches, and help reduce fever
  • Each pain reliever gelcap features laser-drilled holes to quickly release pain medicine and contains 500 mg of acetaminophen for fast, effective extra strength pain relief that works at the speed of life, while being gentle on the stomach
  • Use as a fever reducer and to relieve minor aches and pains including headache, backache, toothache, menstrual and premenstrual cramps, minor pain of arthritis, joint and muscle pain, and pain caused by the common cold and flu
  • With 500 mg of acetaminophen per gelcap, this extra strength oral pain reliever is fast-acting and can be used by adults and children who are 12 years and older
  • Experience relief of minor aches and pains with Tylenol, the #1 doctor recommended brand for pain relief and fever reduction
No. 4
Tylenol 8 Hour Arthritis Pain Tablets with 650 mg Acetaminophen for Arthritis & Joint Pain, 100 ct
  • ARTHRITIS PAIN RELIEF: Tylenol 8HR Arthritis Pain Extended-Release Caplets with 650 mg acetaminophen caplets provides fast-acting, temporary relief of minor arthritis and joint pain targeted in the hands, wrists, knees, ankles, elbows, and feet.
  • ACETAMINOPHEN FORMULA: Each Tylenol 8HR Arthritis Pain relief pill contains 650 mg of acetaminophen in each caplet; For effective pain relief of minor arthritis and joint pains; Effective fever reducer.
  • Tylenol 8HR ARTHRITIS PAIN Relief PILLS: Includes 100 caplets; use 650 mg acetaminophen caplets to help provide Arthritis pain relief; The first layer of the bi-layer pill acts fast to relieve pain, and the second lasts up to 8 hours.
  • HOW To USE: Adults ages 18+, take two arthritis pain relief caplets every 8 hours while symptoms last; Do not exceed 6 capsule in 24 hours unless directed by a doctor.
  • INCLUDES: Pack of 1, 100 Tylenol 8HR Arthritis Pain Extended-Release pain relief caplets; #1 doctor recommended brand for pain relief and fever reduction; When used as directed Tylenol 8HR Arthritis Pain Relief offers an excellent safety profile.
SaleNo. 5
Excedrin Tension Headache Relief Caplets, Acetaminophen 500mg, Caffeine 65mg, Pain Reliever, Aspirin-Free, 100 Count
  • One bottle of 100 caplets of Excedrin Tension Headache Relief Caplets Without Aspirin for Head, Neck and Shoulder Pain Relief
  • Aspirin-free tension headache pain medicine that quickly relieves headaches and pain caused by tension and stress
  • Delivers muscle ache, shoulder and neck pain relief
  • Combines acetaminophen with caffeine to temporarily relieve pain caused by headaches and muscle aches
  • Contains a trusted formula that combines a pain reliever and an amplifier
  • Effectively relieves tension-type headaches in convenient caplet form
  • HSA and FSA eligible product
SaleNo. 6
Aleve Pain Relief Naproxen Sodium Caplets ‐ 50 Count
  • Up to 12-Hours of Uninterrupted Pain Relief: Aleve Caplets provide long-lasting pain relief of minor arthritis, headache, and back pain
  • Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
  • Targeted Pain Relief: Every tablet is made with 220 mg of naproxen sodium to help you take on muscle pain and provide back pain relief
  • Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
  • Comes in small, easy-to-swallow tablets; use as directed
No. 7
Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count
  • ACTIVE INGREDIENT: Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg active ingredient is acetaminophen 650 mg,. Compare to the active ingredient in Tylenol 8HR Arthritis Pain.
  • PURPOSE: Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg is a pain reliever and fever reducer that can be used for the temporary relief of minor pain of arthritis.
  • TEMPORARY PAIN RELIEF: This product may also be used to temporarily relieve other minor aches and pains due to: muscular aches, backache, premenstrual and menstrual cramps, the common cold, headache, toothache.
  • ASPIRIN FREE, GLUTEN FREE: Extended release caplets (capsule-shaped tablets) each provide 650 mg of acetaminophen, pain reliever and fever reducer, and contain no aspirin. Effective for minor arthritis pain. This product is gluten free.
  • PUSH & TURN CAP: The container has a child-resistant cap. This product is a pain reliever and fever reducer for adults. Under 18 years of age, ask a doctor.
SaleNo. 8
Tylenol Extra Strength Dissolve Packs, 500 mg Acetaminophen Pain Reliever & Fever Reducer, On-The-Go Powder Packets for Minor Aches & Pains, Ibuprofen- & Aspirin-Free, Berry Flavor, 32 ct
  • 32-count of Tylenol Extra Strength Dissolve Packs with acetaminophen pain reliever and fever reducer features a great tasting Berry flavor and temporarily relieves minor aches and pains for adults and children 12+
  • This dissolving powder medicine temporarily provides relief from minor aches and pains due to the common cold or flu, headache, shoulder or knee pain, backache, muscle aches, minor pain of arthritis, menstrual cramps and toothache
  • Each oral pain reliever powder packet contains the maximum strength, 500 milligrams of acetaminophen, a safe and effective pain reliever and fever reducer, and is both ibuprofen-free and aspirin-free
  • No water, no problem. This portable pain medicine powder dissolves in seconds on the tongue with no water needed, is indicated for both adults and children 12 years of age and older & is safe when used as directed
  • From the #1 doctor recommended brand for pain relief and fever reduction, experience extra strength pain relief in a berry-flavored medicine that comes in a convenient on-the-go form to have on hand whenever pain hits
SaleNo. 9
Amazon Basic Care - Extra Strength Acetaminophen Caplet 500 mg, 100 Count ( 50 pouches of 2 caplets )
  • ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg's active ingredient is acetaminophen 500 mg. Compare to the active ingredient of Extra Strength Tylenol Caplets.
  • PAIN RELIEVER AND FEVER REDUCER: Temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps Also temporarily reduces fever
  • EASY TO SWALLOW: Count on these easy-to-swallow caplets for fast-acting headache and fever relief. Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg may be used as a pain reliever and fever reducer for adults and children 12 years and over.
  • EXTRA STRENGTH PAIN RELIEF: When pain has you in its grips, even small tasks can be tough Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg provides strong, fast pain relief in convenient travel size packs for when you're on the go
  • ASPIRIN AND CAFFEINE FREE Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg provides the pain relief and fever reduction you need and is safe when taken as directed This product is gluten free

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Last update on 2025-07-04 / Affiliate links / Images from Amazon Product Advertising API